Jarvis D, Chinn S, Sterne J, Luczynska C, Burney P
Dept of Public Health Medicine, United Medical and Dental Schools, St Thomas Campus, London, UK.
Eur Respir J. 1998 Mar;11(3):651-8.
The association of respiratory symptoms and lung function with the use of gas for cooking was examined using data collected as part of the European Community Respiratory Health Survey, an international multicentre study. Associations between gas cooking and respiratory symptoms and respiratory function were assessed by logistic and multiple regression models. Tests for interaction were used to examine whether the effect of gas cooking varied between centres and, as there was evidence for this, the average effects were estimated using standard methods for random effects meta-analysis. Data from 5,561 males and 6,029 females living in 23 centres in 11 countries were analysed. There was no significant association found between respiratory symptoms and gas cooking in males. In females the association between some respiratory symptoms and gas cooking varied between centres with an overall positive association with "wheeze in the last 12 months" (odds ratio (OR) 1.24: 95% confidence interval (95% CI) 1.00-1.54) and "wheeze with breathlessness in the last 12 months" (OR 1.33: 95% CI 1.06-1.69). There was no evidence that atopy modified this association. Cooking with gas was associated with airways obstruction in both males and females although the differences failed to reach statistical significance. In some countries the use of gas for cooking is associated with respiratory symptoms suggestive of airways obstruction in females.
利用作为欧洲共同体呼吸健康调查(一项国际多中心研究)一部分收集的数据,研究了呼吸症状和肺功能与使用燃气烹饪之间的关联。通过逻辑回归和多元回归模型评估燃气烹饪与呼吸症状及呼吸功能之间的关联。采用交互作用检验来考察燃气烹饪的影响在各中心之间是否存在差异,鉴于有证据表明存在这种差异,使用随机效应荟萃分析的标准方法估计平均效应。对来自11个国家23个中心的5561名男性和6029名女性的数据进行了分析。在男性中,未发现呼吸症状与燃气烹饪之间存在显著关联。在女性中,某些呼吸症状与燃气烹饪之间的关联在各中心之间存在差异,总体上与“过去12个月内喘息”(优势比(OR)1.24:95%置信区间(95%CI)1.00 - 1.54)和“过去12个月内喘息伴呼吸急促”(OR 1.33:95%CI 1.06 - 1.69)呈正相关。没有证据表明特应性会改变这种关联。无论男性还是女性,使用燃气烹饪都与气道阻塞有关,尽管差异未达到统计学显著性。在一些国家,使用燃气烹饪与女性提示气道阻塞的呼吸症状有关。