Morton S L, Moeller P D, Young K A, Lanoue B
Center for Culture Marine Phytoplankton, Bigelow Laboratory for Ocean Science, Harbor, ME 04575, USA.
Toxicon. 1998 Jan;36(1):201-6. doi: 10.1016/s0041-0101(97)00054-8.
A species of epiphytic Prorocentrum (Dinophyta, Prorocentrales, collected from the macroalga Dictyota dichotoma, was brought into culture. Based on morphological characteristics, this isolate was identified as Prorocentrum belizeanum. Analysis of the culture extract using high-performance liquid chromatography and liquid chromatography-mass spectrometry indicated the production of okadaic acid, a toxic polyether linked with the human diseases, diarrhetic shellfish poisoning and ciguatera fish poisoning.
从大型海藻二叉网翼藻(Dictyota dichotoma)上采集到一种附生的原甲藻属(甲藻门,原甲藻目)物种,并将其进行培养。基于形态特征,该分离物被鉴定为伯利兹原甲藻(Prorocentrum belizeanum)。使用高效液相色谱和液相色谱 - 质谱联用对培养提取物进行分析表明产生了冈田酸,这是一种与人类疾病腹泻性贝类中毒和雪卡毒素中毒相关的有毒聚醚。