吸烟对人晶状体中铜、铅和镉蓄积的影响。
Effect of cigarette smoking on copper, lead, and cadmium accumulation in human lens.
作者信息
Cekic O
机构信息
Department of Ophthalmology, University of Ankara Medical School, Turkey.
出版信息
Br J Ophthalmol. 1998 Feb;82(2):186-8. doi: 10.1136/bjo.82.2.186.
Abstract
AIM
To identify cigarette smoking as a risk factor for development of cataract, to determine the importance of copper, lead, and cadmium in cataractogenesis, and to learn about any relation between those elements.
METHODS
Copper, lead, and cadmium concentrations were measured by atomic absorption spectrophotometry in 37 cataractous and nine normal human lenses.
RESULTS
All three element accumulations in lenses with cataract were statistically meaningful. Lenticular copper, lead, and cadmium were increased significantly with cigarette smoking. Cadmium had a positive correlation both with lead and copper in cataractous lenses.
CONCLUSION
The accumulation of copper, lead, and cadmium occurs in cataract. The probable source of cadmium in humans is cigarettes. Lenticular cadmium accumulation also increases copper and lead precipitation in the lens. Cigarette smoking might be cataractogenic.
摘要
目的
确定吸烟是否为白内障发生的危险因素，明确铜、铅和镉在白内障形成过程中的重要性，并了解这些元素之间的关系。
方法
采用原子吸收分光光度法测量37例白内障患者和9例正常人晶状体中铜、铅和镉的浓度。
结果
白内障晶状体中这三种元素的蓄积均具有统计学意义。晶状体中的铜、铅和镉随吸烟量显著增加。在白内障晶状体中，镉与铅和铜均呈正相关。
结论
白内障中存在铜、铅和镉的蓄积。人体中镉的可能来源是香烟。晶状体中镉的蓄积也会增加晶状体中铜和铅的沉淀。吸烟可能致白内障。
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