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滑雪旅馆中青少年群体甲型流感爆发。

Influenza A outbreak among adolescents in a ski hostel.

作者信息

Lyytikäinen O, Hoffmann E, Timm H, Schweiger B, Witte W, Vieth U, Ammon A, Petersen L R

机构信息

Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.

出版信息

Eur J Clin Microbiol Infect Dis. 1998 Feb;17(2):128-30. doi: 10.1007/BF01682171.

DOI:10.1007/BF01682171
PMID:9629981
Abstract

An outbreak of influenza A H3N2 with a high attack rate (49%) and abrupt onset (69% became ill within 2 days) occurred among 81 ski school participants who stayed in a crowded hostel in Austria in early 1997. Two students were hospitalized with pneumonia; one of them died. Cultures of blood and/or respiratory secretions from the hospitalized students yielded toxin-producing Staphylococcus aureus. Influenza A H3N2 was confirmed serologically in four participants, including one surviving hospitalized student, and by polymerase chain reaction of lung tissue from the deceased student. This investigation demonstrates that influenza can cause an explosive outbreak among skiers in a crowded hostel, leading to severe complications among previously healthy adolescents.

摘要

1997年初,81名在奥地利一家拥挤旅舍住宿的滑雪学校学员中爆发了甲型H3N2流感,发病率很高(49%)且起病突然(69%在2天内发病)。两名学生因肺炎住院;其中一人死亡。住院学生的血液和/或呼吸道分泌物培养出产毒素的金黄色葡萄球菌。通过血清学方法在4名参与者中确诊为甲型H3N2流感,其中包括一名幸存的住院学生,并且通过对死亡学生的肺组织进行聚合酶链反应确诊。这项调查表明,流感可在拥挤旅舍的滑雪者中引发爆发,导致原本健康的青少年出现严重并发症。

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