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[根据辐射剂量对切尔诺贝利核电站30公里区域工作人员的免疫状态指标、α-1胸腺素水平及胸腺上皮细胞自身抗体水平的研究]

[Study of immune status indices, levels of alpha-1-thymosin and autoantibodies to thymic epithelial cells in persons who worked in the 30-kilometer zone of the Chernobyl AES depending on the radiation dose].

作者信息

Titova L D, Sharova N I

机构信息

Institute of Immunology, Ministry of Health of Russian Federation, Moscow.

出版信息

Radiats Biol Radioecol. 1998 Mar-Apr;38(2):215-22.

PMID:9633624
Abstract

The indices of immune status, concentration of alpha 1-thymosin and level of thymus epithelial cell autoantibodies in human blood of persons, who had worked in 30-km zone Chernobyl NPP were studied. The decrease in mean number of leukocytes, lymphocytes, CD5+, CD4+, CD8+ cells, content of serum alpha 1-thymosin and increased level of autoantibodies were detected in workers, whose dose rates irradiation were greater than 25 cSv. So, the quality differences in the changes of immune system, which were induced by low dose chronic irradiation were obtained.

摘要

对曾在切尔诺贝利核电站30公里区域工作的人员的人体血液中的免疫状态指标、α1-胸腺素浓度和胸腺上皮细胞自身抗体水平进行了研究。在剂量率照射大于25 cSv的工人中,检测到白细胞、淋巴细胞、CD5 +、CD4 +、CD8 +细胞的平均数量减少,血清α1-胸腺素含量降低,自身抗体水平升高。因此,获得了低剂量慢性照射引起的免疫系统变化的质量差异。

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