Xiong Y, Wu T, Zhang Y, Tanguay R M, Nicole L, Yuan Y, Zhang G
Hankou Airplane Hospital No. 457, Wuhan.
J Tongji Med Univ. 1997;17(2):83-5. doi: 10.1007/BF02888240.
Comparison in the heart rate, oral temperature and lymphocyte DNA damage during heat stress was made in pilots with negative antibodies to heat stress proteins (HSPs) and those with positive antibodies in the man-made climate room with Western blot and comet assay. Our results showed that the increase in oral temperature, heart rate and lymphocyte DNA damage in pilots with the positive antibodies to HSPs were higher than those in pilots with the negative antibodies during heat stress. These results indicated that the presence of autoantibodies in plasma of pilots might reflect heat damage and high sensitivity to heat.
在人工气候室中，运用蛋白质免疫印迹法和彗星试验，对热应激蛋白（HSPs）抗体阴性和阳性的飞行员在热应激期间的心率、口腔温度及淋巴细胞DNA损伤进行了比较。我们的结果显示，热应激期间，HSPs抗体阳性的飞行员口腔温度、心率的升高以及淋巴细胞DNA损伤程度均高于HSPs抗体阴性的飞行员。这些结果表明，飞行员血浆中自身抗体的存在可能反映热损伤以及对热的高敏感性。
