Drossman D A, Li Z, Andruzzi E, Temple R D, Talley N J, Thompson W G, Whitehead W E, Janssens J, Funch-Jensen P, Corazziari E
University of North Carolina, Division of Digestive Diseases, Chapel Hill 27599-7080.
Dig Dis Sci. 1993 Sep;38(9):1569-80. doi: 10.1007/BF01303162.
Our objective was to obtain national data of the estimated prevalence, sociodemographic relationships, and health impact of persons with functional gastrointestinal disorders. We surveyed a stratified probability random sample of U.S. householders selected from a data base of a national market firm (National Family Opinion, Inc.). Questions were asked about bowel symptoms, sociodemographic associations, work absenteeism, and physician visits. The sampling frame was constructed to be demographically similar to the U.S. householder population based on geographic region, age of householder, population density, household income, and household size. Of 8250 mailings, 5430 were returned suitable for analysis (66% response). The survey assessed the prevalence of 20 functional gastrointestinal syndromes based on fulfillment of multinational diagnostic (Rome) criteria. Additional variables studied included: demographic status, work absenteeism, health care use, employment status, family income, geographic area of residence, population density, and number of persons in household. For this sample, 69% reported having at least one of 20 functional gastrointestinal syndromes in the previous three months. The symptoms were attributed to four major anatomic regions: esophageal (42%), gastroduodenal (26%), bowel (44%), and anorectal (26%), with considerable overlap. Females reported greater frequencies of globus, functional dysphagia, irritable bowel syndrome, functional constipation, functional abdominal pain, functional biliary pain and dyschezia; males reported greater frequencies of aerophagia and functional bloating. Symptom reporting, except for incontinence, declines with age, and low income is associated with greater symptom reporting. The rate of work/school absenteeism and physician visits is increased for those having a functional gastrointestinal disorder. Furthermore, the greatest rates are associated with those having gross fecal incontinence and certain more painful functional gastrointestinal disorders such as chronic abdominal pain, biliary pain, functional dyspepsia and IBS. Preliminary information on the prevalence, socio-demographic features and health impact is provided for persons who fulfill diagnostic criteria for functional gastrointestinal disorders.
我们的目标是获取有关功能性胃肠疾病患者的估计患病率、社会人口学关系及健康影响的全国性数据。我们从一家全国性市场公司(国家家庭意见公司)的数据库中选取了美国家庭住户的分层概率随机样本进行调查。询问了有关肠道症状、社会人口学关联、旷工情况及就医情况的问题。抽样框架的构建旨在使其在地理区域、住户年龄、人口密度、家庭收入及家庭规模方面在人口统计学上与美国家庭住户人口相似。在8250份邮寄调查问卷中,有5430份被退回且适合进行分析(回复率为66%)。该调查根据多国诊断(罗马)标准评估了20种功能性胃肠综合征的患病率。研究的其他变量包括:人口统计学状况、旷工情况、医疗保健利用情况、就业状况、家庭收入、居住地理区域、人口密度及家庭人口数量。对于这个样本,69%的人报告在过去三个月中至少患有一种20种功能性胃肠综合征。这些症状归因于四个主要解剖区域:食管(42%)、胃十二指肠(26%)、肠道(44%)和肛门直肠(26%),存在相当程度的重叠。女性报告有咽部异物感、功能性吞咽困难、肠易激综合征、功能性便秘、功能性腹痛、功能性胆绞痛和排便困难的频率更高;男性报告有吞气症和功能性腹胀的频率更高。除失禁外,症状报告随年龄增长而减少,低收入与更多的症状报告相关。患有功能性胃肠疾病的人旷工/缺课率及就医率会增加。此外,最高比率与那些患有严重大便失禁以及某些更疼痛的功能性胃肠疾病(如慢性腹痛、胆绞痛、功能性消化不良和肠易激综合征)的人相关。本文为符合功能性胃肠疾病诊断标准的人群提供了有关患病率、社会人口学特征及健康影响的初步信息。