厄瓜多尔传统医学中使用的植物的抗炎和抗氧化活性。

Antiinflammatory and antioxidant activity of plants used in traditional medicine in Ecuador.

作者信息

de las Heras B, Slowing K, Benedí J, Carretero E, Ortega T, Toledo C, Bermejo P, Iglesias I, Abad M J, Gómez-Serranillos P, Liso P A, Villar A, Chiriboga X

机构信息

Departamento de Farmacología, Facultad de Farmacia, Universidad Complutense de Madrid, Spain.

出版信息

J Ethnopharmacol. 1998 Jun;61(2):161-6. doi: 10.1016/s0378-8741(98)00029-4.

DOI:10.1016/s0378-8741(98)00029-4

PMID:9683347

Abstract

Ethanolic extracts from 15 plant species, representing eight different families, used in traditional medicine in Ecuador were evaluated for antiinflammatory and antioxidant activities. Conyza floribunda, Eupatorium articulatum, Bonafousia longituba, Bonafousia sananho, Tagetes pusilla and Piper lenticellosum extracts showed a significant antiinflammatory activity in vivo in the carrageenan-induced paw oedema model in mice. The extracts were also tested in vitro for their ability to inhibit lipid peroxidation and to scavenge superoxide and hydroxyl radicals. E. articulatum extract possesses both activities. Baccharis trinervis, E. articulatum and Phytolacca rivinoides extracts were active as antioxidants.

摘要

对来自厄瓜多尔传统医学中15种植物（代表8个不同科）的乙醇提取物进行了抗炎和抗氧化活性评估。多花白酒草、关节泽兰、长管博纳菊、萨纳博纳菊、矮万寿菊和具瘤胡椒提取物在小鼠角叉菜胶诱导的爪肿胀模型中显示出显著的体内抗炎活性。还对提取物进行了体外测试，以评估其抑制脂质过氧化以及清除超氧阴离子和羟自由基的能力。关节泽兰提取物兼具这两种活性。三脉酒神菊、关节泽兰和商陆提取物具有抗氧化活性。