原位杂交：对柔脑膜转移瘤可能具有诊断辅助作用。
In situ hybridization: a possible diagnostic aid in leptomeningeal metastasis.
作者信息
van Oostenbrugge R J, Hopman A H, Ramaekers F C, Twijnstra A
机构信息
Department of Neurology, University Hospital Maastricht, The Netherlands.
出版信息
J Neurooncol. 1998 Jun-Jul;38(2-3):127-33. doi: 10.1023/a:1005926624303.
PMID:9696362
Abstract
In this review we discuss the clinical features and pathophysiology of leptomeningeal metastasis (LM), and elaborate on diagnostic tools for the detection of this serious complication of cancer. Because of the low sensitivity of the cytologic examination, new diagnostic approaches have been developed. The in situ hybridization technique may prove to be a reliable and early test for the detection of LM.
摘要
在本综述中，我们讨论了柔脑膜转移（LM）的临床特征和病理生理学，并详细阐述了用于检测这种严重癌症并发症的诊断工具。由于细胞学检查的敏感性较低，已开发出新的诊断方法。原位杂交技术可能被证明是检测LM的一种可靠且早期的检测方法。
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