枯草芽孢杆菌果糖-1,6-二磷酸酶基因（fbp）的鉴定与表达
Identification and expression of the Bacillus subtilis fructose-1, 6-bisphosphatase gene (fbp).
作者信息
Fujita Y, Yoshida K, Miwa Y, Yanai N, Nagakawa E, Kasahara Y
机构信息
Department of Biotechnology, Faculty of Engineering, Fukuyama University, Fukuyama 729-0292, Japan.
出版信息
J Bacteriol. 1998 Aug;180(16):4309-13. doi: 10.1128/JB.180.16.4309-4313.1998.
Abstract
The Bacillus subtilis fbp gene encoding fructose-1,6-bisphosphatase (FBPase) was originally identified as yydE. The fbp gene was expressed at a fairly constant level in cells undergoing glycolysis or gluconeogenesis. fbp transcription was initiated 94 bp upstream of the translation initiation codon, resulting in a 2.4-kb monocistronic transcript. Interestingly, B. subtilis FBPase exhibited no significant similarity to other FBPases in protein sequence databases.
摘要
编码果糖-1,6-二磷酸酶（FBPase）的枯草芽孢杆菌fbp基因最初被鉴定为yydE。fbp基因在进行糖酵解或糖异生的细胞中以相当恒定的水平表达。fbp转录在翻译起始密码子上游94 bp处起始，产生一个2.4 kb的单顺反子转录本。有趣的是，枯草芽孢杆菌FBPase在蛋白质序列数据库中与其他FBPase没有显著的相似性。
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