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大鼠中溶剂干燥和γ射线辐照的同种异体肌腱移植。力学和形态学评估。

Solvent-dried and gamma-irradiated tendon allografts in rats. Mechanical and morphological evaluation.

作者信息

Maeda A, Horibe S, Matsumoto N, Nakamura N, Mae T, Shino K

机构信息

Department of Orthopaedic Surgery, Osaka University Medical School, Suita, Japan.

出版信息

J Bone Joint Surg Br. 1998 Jul;80(4):731-6. doi: 10.1302/0301-620x.80b4.8174.

DOI:10.1302/0301-620x.80b4.8174
PMID:9699845
Abstract

We examined solvent-dried, gamma-irradiated (SD-R) allografts and fresh-frozen (FF) allografts mechanically and morphologically. Before transplantation, FF grafts were more than six times stronger than SD-R grafts. After four weeks, the tensile strength was about the same in both groups. At 24 weeks only collagen fibrils of small diameter were observed in the SD-R grafts while in FF grafts fibrils of small and intermediate diameter were seen. Clinically, we suggest that SD-R grafts could be used as a favourable alternative to FF grafts if care was taken regarding their initial mechanical weakness.

摘要

我们对经溶剂干燥、γ射线辐照(SD-R)的同种异体移植物和新鲜冷冻(FF)的同种异体移植物进行了力学和形态学检查。移植前,FF移植物的强度比SD-R移植物强六倍多。四周后,两组的拉伸强度大致相同。在24周时,在SD-R移植物中仅观察到小直径的胶原纤维,而在FF移植物中则可见小直径和中等直径的纤维。临床上,我们认为,如果注意到SD-R移植物最初的力学弱点,它们可以作为FF移植物的一个有利替代物。

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引用本文的文献

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Cell Tissue Bank. 2012 Jun;13(2):217-23. doi: 10.1007/s10561-011-9251-7. Epub 2011 Mar 23.