炎症性肠病中的吸烟与尼古丁：对细胞因子有益还是有害？
Smoking and nicotine in inflammatory bowel disease: good or bad for cytokines?
作者信息
Zijlstra F J
机构信息
Department of Pharmacology, Faculty of Medicine and Health Sciences, Erasmus University Rotterdam, The Netherlands.
出版信息
Mediators Inflamm. 1998;7(3):153-5. doi: 10.1080/09629359891072.
Abstract
Smoking has either a beneficial or harmful effect on the course and recurrence of ulcerative colitis and Crohn's disease respectively. Transdermal application of nicotine had similar effects in ulcerative colitis and therefore was considered to be an effective basic drug which could be further developed in the search for new compounds in the treatment of acute exacerbations of corticosteroid resistant ulcerative colitis. In this communication the short-term use of nicotine in ulcerative colitis is reviewed.
摘要
吸烟对溃疡性结肠炎和克罗恩病的病程及复发分别具有有益或有害的影响。尼古丁经皮给药在溃疡性结肠炎中具有类似的作用，因此被认为是一种有效的基础药物，在寻找治疗对皮质类固醇耐药的溃疡性结肠炎急性加重期新化合物的过程中可进一步开发。在本交流中，对尼古丁在溃疡性结肠炎中的短期应用进行了综述。
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本文引用的文献
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