Menet E, Goujon J M, Levillain P, Babin P
Laboratoire d'Anatomopathologie, CHU, Poitiers.
Neurochirurgie. 1997;43(6):357-60.
In this retrospective study (1986-1996), a series of 250 immunocompetent patients (SFNC series) with primary malignant lymphoma of the central nervous system is reviewed and the lymphomas redefined using the REAL (Revised European-American classification of Lymphoid neoplasms) and the modified Kiel classifications. All the tumors available for review were classic diffuse non-Hodgkin's lymphomas. Thirty-eight were unclassifiable due to small size and artifacts in the specimens. Eight cases were of T-cell type (3.7%). The 212 others cases were B-cell type. According to the REAL classification, the high majority was diffuse large cell (62%). Following the modified Kiel classification percentage of cases categorized as low and high grade of malignancy were 22.4% and 77.6% respectively.
在这项回顾性研究(1986 - 1996年)中,对一系列250例具有免疫活性的原发性中枢神经系统恶性淋巴瘤患者(SFNC系列)进行了回顾,并使用REAL(欧美淋巴瘤修订分类)和改良的基尔分类法对淋巴瘤进行重新分类。所有可供检查的肿瘤均为经典弥漫性非霍奇金淋巴瘤。38例因标本体积小和存在假象而无法分类。8例为T细胞型(3.7%)。其他212例为B细胞型。根据REAL分类,绝大多数为弥漫性大细胞型(62%)。按照改良的基尔分类法,归类为低级别和高级别恶性肿瘤的病例百分比分别为22.4%和77.6%。