Brosnan S, Royston B, White D
Department of Anaesthetics, Northwick Park Hospital, Harrow, London, UK.
Anaesthesia. 1998 Jun;53(6):560-4. doi: 10.1046/j.1365-2044.1998.00366.x.
In a series of studies designed to investigate the need for a temperature-compensated vaporiser for use in a circle system, we first studied temperature changes within and isoflurane concentration delivered by a Komesaroff vaporiser during bench tests using different gas flows. Agent temperature and vapour concentration decreased as predicted by the Antoine equation. Using the vaporiser within a circle system during clinical anaesthesia, we then studied 20 patients breathing spontaneously and a further 10 patients receiving controlled ventilation, measuring the temperature of the agent within the vaporiser and the concentration of agent inspired by a the patient. In clincial use with the frest gas flows of 1-3.min-1, the inspired agent concentration did not decrease despite the decrease in temperature of the liquid isoflurane in the vaporiser.
在一系列旨在研究用于循环系统的温度补偿蒸发器必要性的研究中，我们首先在台架试验中使用不同气流研究了科梅萨罗夫蒸发器内部的温度变化以及异氟烷浓度。如安托万方程所预测的那样，麻醉剂温度和蒸汽浓度降低。然后，在临床麻醉期间，我们在循环系统中使用该蒸发器，研究了20例自主呼吸的患者以及另外10例接受控制通气的患者，测量了蒸发器内麻醉剂的温度以及患者吸入的麻醉剂浓度。在临床使用中，新鲜气流为1-3L·min⁻¹时，尽管蒸发器中液态异氟烷的温度降低，但吸入的麻醉剂浓度并未降低。
