Laredo F G, Sanchez-Valverde M A, Cantalapiedra A G, Pereira J L, Agut A
Facultad de Veterinaria, Departamento de Patología Animal, Universidad de Murcia, Spain.
Vet Rec. 1998 Oct 17;143(16):437-40. doi: 10.1136/vr.143.16.437.
The Komesaroff machine is a low-flow, closed-circle circuit with a low resistance vaporiser, of the Goldman type, in circuit. This trial assessed the mechanical consistency of the delivery of isoflurane by the vaporisers, and used six dogs to compare the in vivo cardiorespiratory effects of the anaesthetic agent delivered by the Komesaroff machine with the effects of a circle system with high flows in the semi-closed mode. The delivery of isoflurane was constant for each vaporiser setting and no potentially dangerous concentrations of isoflurane were observed. The mean (sem) percentages of isoflurane were 0.18 (0.019) at setting I, 1.46 (0.055) at setting II, 3.12 (0.066) at setting III and 3.01 (0.047) at setting IV. There were no significant differences between the two types of circuit in vivo, and the measured haemodynamic variables were satisfactory throughout the experiments.
科梅萨罗夫机器是一种低流量、闭环回路，带有一个低阻力蒸发器，属于戈德曼类型，处于回路中。该试验评估了蒸发器输送异氟烷的机械一致性，并使用六只狗比较了科梅萨罗夫机器输送的麻醉剂在体内的心肺效应与半封闭模式下高流量循环系统的效应。对于每个蒸发器设置，异氟烷的输送都是恒定的，并且未观察到潜在危险浓度的异氟烷。异氟烷的平均（标准误）百分比在设置I时为0.18（0.019），在设置II时为1.46（0.055），在设置III时为3.12（0.066），在设置IV时为3.01（0.047）。两种回路类型在体内无显著差异，并且在整个实验过程中测得的血流动力学变量令人满意。
