适用于疫苗用途的1期Q热抗原的制备。
Preparation of phase 1Q fever antigen suitable for vaccine use.
作者信息
Spicer D S, DeSanctis A N
出版信息
Appl Environ Microbiol. 1976 Jul;32(1):85-8. doi: 10.1128/aem.32.1.85-88.1976.
Abstract
Five lots of phase 1 Q fever antigen suitable for use as vaccine were prepared utilizing the Freon-brushite method of antigen purification. Antigen concentration levels were initially adjusted turbidimetrically and later confirmed by antibody response in guinea pigs. Data showed that all lots were essentially identical in purity and antigenicity.
摘要
利用氟利昂-透辉石抗原纯化方法制备了五批适合用作疫苗的1期Q热抗原。抗原浓度水平最初通过比浊法进行调整，随后通过豚鼠的抗体反应进行确认。数据表明，所有批次在纯度和抗原性方面基本相同。
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本文引用的文献
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