Franco J, Blanquer R
Department of Pneumology, Hospital Dr. Peset, Valencia, Spain.
Int J Tuberc Lung Dis. 1998 Aug;2(8):663-9.
Spain has the highest rates in Europe of the acquired immune-deficiency syndrome (AIDS), and probably a high rate of dual human immunodeficiency virus (HIV)/tuberculosis infection.
To determine the trends of tuberculosis mortality in Spain from 1970 to 1993, and to draw conclusions about the effects of the AIDS epidemic on these trends.
Official population figures and data on deaths from tuberculosis were used to calculate specific tuberculosis mortality rates by age and sex (per 100000 population). Causes of death from tuberculosis were grouped according to the International Classification of Diseases.
The crude death rate decreased from 10.28 to 1.84, with an annual mean decrease of 8.1% (95% confidence interval 7.5% to 8.7%). No changes in mortality from tuberculosis of the central nervous system (CNS) have been recorded since 1982, and none in mortality from other tuberculosis and in the age group 20-49 years since 1986. Mortality was higher among males and in the older age groups. The peak observed in the 1970s, due to the excess of deaths from CNS tuberculosis in children under the age of 5 years, has disappeared.
Between 1970 and 1993, tuberculosis mortality in Spain decreased, although an excess of deaths occurred in young adults and from extra-pulmonary tuberculosis, coinciding with the AIDS epidemic.
西班牙是欧洲获得性免疫缺陷综合征（艾滋病）发病率最高的国家，而且可能同时感染人类免疫缺陷病毒（HIV）/结核病的比例也很高。
确定1970年至1993年西班牙结核病死亡率的趋势，并就艾滋病流行对这些趋势的影响得出结论。
使用官方人口数据和结核病死亡数据，按年龄和性别计算特定结核病死亡率（每10万人口）。结核病死亡原因根据国际疾病分类进行分组。
粗死亡率从10.28降至1.84，年均下降8.1%（95%置信区间7.5%至8.7%）。自1982年以来，中枢神经系统（CNS）结核病死亡率没有变化，自1986年以来，其他结核病死亡率以及20至49岁年龄组的死亡率也没有变化。男性和老年人群的死亡率较高。20世纪70年代观察到的高峰，是由于5岁以下儿童中枢神经系统结核病死亡人数过多所致，现已消失。
1970年至1993年期间，西班牙的结核病死亡率有所下降，尽管在年轻人和肺外结核病患者中出现了过多死亡，这与艾滋病流行同时发生。
