Aktekin M, Sargon M F, Cakar P, Celik H H, Firat E
Department of Anatomy, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Okajimas Folia Anat Jpn. 1998 May;75(1):45-53. doi: 10.2535/ofaj1936.75.1_45.
In this study, 20 keratoconus corneal tissue were examined. In TEM examination of the cornea, the epithelium was irregular in thickness. In these epithelial cells, the number of microvilli were decreased and they showed an irregular arrangement. Vesicular degeneration and swelling of the mitochondria were observed in the cytoplasm of these cells. Interepithelial relation was normal and the desmosomes did not show any pathology. In the electron microscopic examination of the stroma, focal degeneration was observed in the collagen fibers. In SEM examination of the cornea, depressions and elevations were found on the epithelial surface. Additionally, degenerated epithelial cells were observed on focal areas. To our knowledge, the decreased number of microvilli and their irregular arrangement which we observed in TEM examination of the cornea epithelium were not reported in the literature.
在本研究中，对20份圆锥角膜组织进行了检查。在角膜的透射电子显微镜（TEM）检查中，上皮层厚度不均。在这些上皮细胞中，微绒毛数量减少且排列不规则。在这些细胞的细胞质中观察到线粒体呈水泡样变性和肿胀。上皮细胞间关系正常，桥粒未显示任何病变。在基质的电子显微镜检查中，观察到胶原纤维有局灶性变性。在角膜的扫描电子显微镜（SEM）检查中，上皮表面发现有凹陷和隆起。此外，在局部区域观察到变性的上皮细胞。据我们所知，我们在角膜上皮的TEM检查中观察到的微绒毛数量减少及其不规则排列在文献中尚未见报道。
