Bernasconi O, Auer C, Zografos L, Herbort C P
Department of Ophthalmology, Hôpital Jules Gonin, University of Lausanne, Switzerland.
Graefes Arch Clin Exp Ophthalmol. 1998 Aug;236(8):635-8. doi: 10.1007/s004170050134.
To analyze indocyanine green angiography (ICGA) features in two cases of sympathetic ophthalmia using a standard angiography protocol for posterior uveitis.
Report on two patients who suffered from penetrating ocular injuries 45 and 8 years before sympathetic ophthalmia was diagnosed and confirmed by histopathological examination of the enucleated eye. In addition to routine examination and fluorescein angiography, initial and follow-up ICGAs were performed.
The first patient, with a phthisic right eye following s shotgun injury, consulted 6 months after cataract extraction in his good left eye for progressive visual loss due to a neovascular membrane in a moderately inflamed eye. The second patient consulted 8 years after a perforating injury of his right eye by a metallic foreign body because of recent visual loss and inflammation in his good left eye. ICGA of both patients showed numerous hypofluorescent dark dots visible at the intermediate phase, some becoming isofluorescent at the late phase and resolving after long-term corticosteroid therapy, others remaining hypofluorescent until the late phase.
The two patterns of hypofluorescent areas, either persisting throughout angiography or fading in the late phase, were interpreted respectively as cicatricial and active lesions. ICGA gave determining additional information on choroidal involvement and on subsequent evolution of lesions.
采用后葡萄膜炎的标准血管造影方案，分析两例交感性眼炎的吲哚菁绿血管造影（ICGA）特征。
报告两例患者，在交感性眼炎确诊前45年和8年分别发生穿透性眼外伤，并通过摘除眼球的组织病理学检查得以证实。除了常规检查和荧光素血管造影外，还进行了初始和随访ICGA检查。
第一例患者，右眼因霰弹枪伤而眼球痨，在其健康的左眼白内障摘除术后6个月就诊，因中度炎症眼中的新生血管膜导致视力进行性下降。第二例患者在右眼被金属异物穿孔伤8年后就诊，因其健康的左眼近期出现视力下降和炎症。两名患者的ICGA均显示在中期可见大量低荧光暗点，一些在晚期变为等荧光并在长期皮质类固醇治疗后消退，另一些直至晚期仍保持低荧光。
低荧光区的两种模式，即在整个血管造影过程中持续存在或在晚期消退，分别被解释为瘢痕性和活动性病变。ICGA为脉络膜受累及病变的后续演变提供了决定性的额外信息。
