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[法国图卢兹两例不明原因的本地疟疾]

[Two cases of inexplicable autochthonous malaria in Toulouse, France].

作者信息

Baixench M T, Suzzoni-Blatger J, Magnaval J F, Lareng M B, Larrouy G

机构信息

Laboratoire de Parasitologie, Centre Hospitalier Universitaire Purpan, Toulouse, France.

出版信息

Med Trop (Mars). 1998;58(1):62-4.

PMID:9718558
Abstract

Malaria involving both Plasmodium falciparum and vivax was observed in two patients hospitalized in the same room of the Cardiology Department of the Purpan University Hospital in Toulouse, France. One patient was in coma without fever by the time of diagnosis. None of the patients had traveled to malaria areas within the last 33 years. Epidemiological investigations failed to detect malaria in family members, hospital staff, or other patients. Transmission due to transfusion of infected blood, use of contaminated surgical instrumentation, or bite of an autochthonous anopheles mosquito was reasonable ruled out. Since Toulouse International Airport is located less than three kilometers from the Purpan University Hospital, the most likely explanation was airport-acquired malaria due to the bite of a mosquito imported by an aircraft coming from abroad. The hypothesis that an Anopheles mosquito survived the plane trip and then was blown into the patients' room was supported by temperature and wind conditions prevailing at the time of infection.

摘要

在法国图卢兹的普尔潘大学医院心脏病科同一病房住院的两名患者中,观察到了同时感染恶性疟原虫和间日疟原虫的疟疾病例。其中一名患者确诊时处于昏迷状态且无发热症状。在过去33年内,这两名患者均未前往过疟疾流行地区。流行病学调查未在家庭成员、医院工作人员或其他患者中检测到疟疾。合理排除了因输入感染血液、使用受污染的手术器械或当地按蚊叮咬导致传播的可能性。由于图卢兹国际机场距离普尔潘大学医院不到三公里,最有可能的解释是由来自国外的飞机带入的蚊子叮咬导致的机场获得性疟疾。感染发生时的温度和风况支持了这样一种假设,即一只按蚊在飞机旅行中存活下来,然后被吹进了患者的病房。

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