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血清胆汁酸与结直肠癌的危险因素

Serum bile acids and risk factors for colorectal cancer.

作者信息

van Faassen A, Tangerman A, Bueno-de-Mesquita B H

机构信息

Department of Urology, University Hospital, PO Box 5800, Maastricht 6202 AZ, The Netherlands.

出版信息

Br J Cancer. 2004 Feb 9;90(3):632-4. doi: 10.1038/sj.bjc.6601608.

DOI:10.1038/sj.bjc.6601608
PMID:14760376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2409603/
Abstract

The ratio of deoxycholic acid to chenodeoxycholic acid in the serum of 62 men was inversely related to body mass index and to saturated fat intake after adjustment for body mass index, smoking, and age conversely, this ratio was associated positively with the intake of fibre from grains.

摘要

62名男性血清中脱氧胆酸与鹅去氧胆酸的比例,在对体重指数、吸烟情况和年龄进行校正后,与体重指数及饱和脂肪摄入量呈负相关;相反,该比例与谷物纤维摄入量呈正相关。

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Serum bile acids and risk factors for colorectal cancer.血清胆汁酸与结直肠癌的危险因素
Br J Cancer. 2004 Feb 9;90(3):632-4. doi: 10.1038/sj.bjc.6601608.
2
Effect of ageing on postprandial conjugated and unconjugated serum bile acid levels in healthy subjects.衰老对健康受试者餐后血清结合型和非结合型胆汁酸水平的影响。
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Radioimmunoassay of conjugated cholic acid, chenodeoxycholic acid, and deoxycholic acid from human serum, with use of 125I-labeled ligands.利用125I标记配体对人血清中结合胆酸、鹅去氧胆酸和脱氧胆酸进行放射免疫测定。
Clin Chem. 1979 Feb;25(2):264-8.
4
Decreased concentrations of deoxycholic acid in serum of uraemic patients with diarrhoea.腹泻型尿毒症患者血清中脱氧胆酸浓度降低。
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Simultaneous determination of pool sizes and fractional turnover rates, of deoxycholic acid, cholic acid and chenodeoxycholic acid in man by isotope dilution with 2H and 13C labels and serum sampling.通过用2H和13C标记进行同位素稀释以及血清采样同时测定人体中脱氧胆酸、胆酸和鹅去氧胆酸的池大小和分数周转率。
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Prediction of the bile acid composition of bile from serum bile acid analysis during gallstone dissolution therapy.在胆结石溶解治疗期间,通过血清胆汁酸分析预测胆汁的胆汁酸组成。
Gastroenterology. 1980 Feb;78(2):220-5.
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Assay of the major bile acids in serum by isotope dilution-mass spectrometry.采用同位素稀释质谱法测定血清中的主要胆汁酸。
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Changes in serum bile acids in normal human subjects following the adoption of a low-fat diet.正常人类受试者采用低脂饮食后血清胆汁酸的变化。
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Serum bile acids in patients with hyperlipidaemia.高脂血症患者的血清胆汁酸
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Portal venous bile acids in cholesterol gallstone disease: effect of treatment with chenodeoxycholic and cholic acids.胆固醇结石病中门静脉胆汁酸:鹅去氧胆酸和胆酸治疗的效果
Hepatology. 1985 Jul-Aug;5(4):661-5. doi: 10.1002/hep.1840050423.

引用本文的文献

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Bile acid distributions, sex-specificity, and prognosis in colorectal cancer.胆汁酸分布、性别特异性与结直肠癌预后
Biol Sex Differ. 2022 Oct 23;13(1):61. doi: 10.1186/s13293-022-00473-9.
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Production of New Microbially Conjugated Bile Acids by Human Gut Microbiota.人肠道微生物群产生新型微生物结合胆酸。
Biomolecules. 2022 May 11;12(5):687. doi: 10.3390/biom12050687.
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Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions.超越癌症基因:结直肠癌作为由分子相互作用形成的稳健内在状态。
Open Biol. 2017 Nov;7(11). doi: 10.1098/rsob.170169.

本文引用的文献

1
The effect of the level of dietary calcium and magnesium on the digestibility of fatty acids, simple triglycerides and some natural and hydrogenated fats.膳食钙和镁水平对脂肪酸、简单甘油三酯以及一些天然脂肪和氢化脂肪消化率的影响。
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Diet, body weight, and colorectal cancer: a summary of the epidemiologic evidence.饮食、体重与结直肠癌:流行病学证据综述
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A prospective study of serum bile acid concentrations and colorectal cancer risk in post-menopausal women on the island of Guernsey.根西岛绝经后女性血清胆汁酸浓度与结直肠癌风险的前瞻性研究。
Br J Cancer. 2002 Jun 5;86(11):1741-4. doi: 10.1038/sj.bjc.6600340.
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Bile acids, fibre and colon cancer: the story unfolds.胆汁酸、纤维与结肠癌:故事正在展开。
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5
Limited effect of consumption of uncooked (RS2) or retrograded (RS3) resistant starch on putative risk factors for colon cancer in healthy men.食用未煮熟的(RS2)或回生的(RS3)抗性淀粉对健康男性结肠癌潜在风险因素的影响有限。
Am J Clin Nutr. 1998 Feb;67(2):322-31. doi: 10.1093/ajcn/67.2.322.
6
The Dutch EPIC food frequency questionnaire. II. Relative validity and reproducibility for nutrients.荷兰EPIC食物频率问卷。II. 营养素的相对有效性和可重复性。
Int J Epidemiol. 1997;26 Suppl 1:S49-58. doi: 10.1093/ije/26.suppl_1.s49.
7
Plasma deoxycholic acid is related to deoxycholic acid in faecal water.血浆脱氧胆酸与粪便水中的脱氧胆酸有关。
Cancer Lett. 1997 Mar 19;114(1-2):293-4. doi: 10.1016/s0304-3835(97)04683-1.
8
Effect of ageing on postprandial conjugated and unconjugated serum bile acid levels in healthy subjects.衰老对健康受试者餐后血清结合型和非结合型胆汁酸水平的影响。
Eur J Clin Invest. 1993 Mar;23(3):192-8. doi: 10.1111/j.1365-2362.1993.tb00761.x.
9
Increased serum deoxycholic acid levels in men with colorectal adenomas.患有结肠直肠腺瘤的男性血清脱氧胆酸水平升高。
Gastroenterology. 1993 Jan;104(1):145-51. doi: 10.1016/0016-5085(93)90846-5.
10
Faecal excretion of bile acids and neutral steroids on diets differing in type and amount of dietary fat in young healthy persons.年轻健康人群食用脂肪类型和量不同的饮食时胆汁酸和中性类固醇的粪便排泄情况。
Eur J Clin Invest. 1983 Apr;13(2):115-22. doi: 10.1111/j.1365-2362.1983.tb00075.x.