Kenyon R H, Williams R G, Oster C N, Pedersen C E
J Clin Microbiol. 1978 Jul;8(1):102-4. doi: 10.1128/jcm.8.1.102-104.1978.
Prophylactic treatment of Rocky Mountain spotted fever with a single dose of oxytetracycline was investigated in guinea pigs. Disease was prevented when treatment was administered shortly before expected onset. Relapses occurred when treatment preceded expected onset by 48 h or more.
在豚鼠身上研究了用单剂量土霉素预防性治疗落基山斑疹热。在预期发病前不久给药时可预防疾病。当治疗比预期发病提前48小时或更长时间时会出现复发。