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Prophylactic treatment of Rocky Mountain spotted fever.落基山斑疹热的预防性治疗。
J Clin Microbiol. 1978 Jul;8(1):102-4. doi: 10.1128/jcm.8.1.102-104.1978.
2
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Rocky Mountain spotted fever vaccine: a regional need.落基山斑疹热疫苗：一项地区需求。
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Evaluation of a killed Rocky Mountain spotted fever vaccine in cynomolgus monkeys.食蟹猴中一种灭活落基山斑疹热疫苗的评估
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Rocky Mountain spotted fever vaccine in an animal model.落基山斑疹热疫苗在动物模型中的研究
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In vitro guinea pig leukocyte reactions to Rickettsia rickettsii.豚鼠白细胞对立氏立克次体的体外反应。
Infect Immun. 1977 Dec;18(3):840-6. doi: 10.1128/iai.18.3.840-846.1977.

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本文引用的文献

1
CHLORAMPHENICOL (CHLOROMYCETIN) IN THE TREATMENT OF TSUTSUGAMUSHI DISEASE (SCRUB TYPHUS).氯霉素（氯霉索）治疗恙虫病（丛林斑疹伤寒）
J Clin Invest. 1949 Sep;28(5 Pt 2):1196-215. doi: 10.1172/JCI102154.
2
The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae.某些盐类、氨基酸、糖类及蛋白质对立克次氏体稳定性的影响。
J Bacteriol. 1950 Apr;59(4):509-22. doi: 10.1128/jb.59.4.509-522.1950.
3
Plaque assay for Rickettsia rickettsii.立氏立克次体的噬斑测定
J Bacteriol. 1969 May;98(2):398-402. doi: 10.1128/jb.98.2.398-402.1969.
4
Treatment of epidemic typhus. A comparative study of chloramphenicol, trimethoprim-sulphamethoxazole and doxycycline.流行性斑疹伤寒的治疗。氯霉素、甲氧苄啶-磺胺甲恶唑和多西环素的比较研究。
Trans R Soc Trop Med Hyg. 1973;67(5):718-21. doi: 10.1016/0035-9203(73)90043-6.
5
A microagglutination technique for detection and measurement of rickettsial antibodies.一种用于检测和测量立克次氏体抗体的微量凝集技术。
Acta Virol. 1969 Jan;13(1):60-6.
6
Single-dose doxycycline treatment of louse-borne relapsing fever and epidemic typhus.单剂量强力霉素治疗虱传回归热和流行性斑疹伤寒。
Lancet. 1974 Sep 28;2(7883):742-4. doi: 10.1016/s0140-6736(74)90940-4.
7
Rocky Mountain spotted fever: epidemiology of an increasing problem.落基山斑疹热：一个日益严重问题的流行病学
Ann Intern Med. 1976 Jun;84(6):732-9. doi: 10.7326/0003-4819-84-6-732.
8
Functional and morphologic changes during experimental Rocky Mountain spotted fever in guinea pigs.豚鼠实验性落基山斑疹热期间的功能和形态学变化。
Lab Invest. 1976 Sep;35(3):235-45.
9
In vitro guinea pig leukocyte reactions to Rickettsia rickettsii.豚鼠白细胞对立氏立克次体的体外反应。
Infect Immun. 1977 Dec;18(3):840-6. doi: 10.1128/iai.18.3.840-846.1977.

落基山斑疹热的预防性治疗。

Prophylactic treatment of Rocky Mountain spotted fever.

作者信息

Kenyon R H, Williams R G, Oster C N, Pedersen C E

出版信息

J Clin Microbiol. 1978 Jul;8(1):102-4. doi: 10.1128/jcm.8.1.102-104.1978.

DOI:10.1128/jcm.8.1.102-104.1978
PMID:97307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC275128/
Abstract

Prophylactic treatment of Rocky Mountain spotted fever with a single dose of oxytetracycline was investigated in guinea pigs. Disease was prevented when treatment was administered shortly before expected onset. Relapses occurred when treatment preceded expected onset by 48 h or more.

摘要

在豚鼠身上研究了用单剂量土霉素预防性治疗落基山斑疹热。在预期发病前不久给药时可预防疾病。当治疗比预期发病提前48小时或更长时间时会出现复发。