Koh E T, Seow A, Pong L Y, Koh W H, Chan L, Howe H S, Lim T H, Low C K
Department of Rheumatology and Immunology, Tan Tock Seng Hospital, Singapore.
J Rheumatol. 1998 Sep;25(9):1705-8.
The Health Assessment Questionnaire - Disability Index (HAQ), used as a disability and outcome measurement in rheumatoid arthritis (RA), has been validated in several languages, but not in Chinese. Our aim was to validate the Chinese version of HAQ (Chinese-HAQ) to suit the needs of Chinese speaking patients with RA in an Asian setting.
The original HAQ was modified in the context of Chinese culture and translated into Chinese by 2 translators aware of the objective of the questionnaire. The Chinese HAQ was self-administered by 42 patients with RA during their routine followup visit and one week later.
The test-retest reliability assessed using Spearman's correlation coefficient was 0.84. Between dimensions measured in the HAQ, the highest test-retest reliability was observed for walking (Spearman correlation coefficient rs=0.80) and the lowest was for eating (rs=0.54). The internal consistency of the scale using Cronbach's alpha was high at 0.86. In terms of criterion validity, the Chinese-HAQ score was found to correlate well with American College of Rheumatology functional status (rs=0.501, p=0.01). The Chinese-HAQ scores also correlated well with markers of disease activity such as patient's perception of pain measured on a visual analog scale (rs=0.55, p < 0.001), grip strength in mm Hg (rs=-0.55. p < 0.001 ), and physician's assessment of disease activity (rs=0.59, p < 0.001).
The Chinese HAQ is a reliable and valid instrument for studies measuring disability of patients with RA in Singapore.
健康评估问卷-残疾指数（HAQ）用于类风湿关节炎（RA）的残疾和结局测量，已在多种语言中得到验证，但未在中国进行验证。我们的目的是验证中文版HAQ（Chinese-HAQ），以满足亚洲背景下说中文的RA患者的需求。
原始HAQ在中国文化背景下进行修改，并由两名了解问卷目的的翻译人员翻译成中文。42例RA患者在常规随访期间自行填写Chinese-HAQ，并在一周后再次填写。
使用Spearman相关系数评估的重测信度为0.84。在HAQ测量的各维度之间，步行的重测信度最高（Spearman相关系数rs=0.80），进食的重测信度最低（rs=0.54）。使用Cronbach's alpha计算的量表内部一致性较高，为0.86。在效标效度方面，发现Chinese-HAQ评分与美国风湿病学会功能状态密切相关（rs=0.501，p=0.01）。Chinese-HAQ评分还与疾病活动标志物密切相关，如视觉模拟量表上测量的患者疼痛感知（rs=0.55，p<0.001）、以毫米汞柱为单位的握力（rs=-0.55，p<0.001）以及医生对疾病活动的评估（rs=0.59，p<0.001）。
Chinese-HAQ是用于测量新加坡RA患者残疾情况研究的可靠且有效的工具。
