德国西南部蓖麻硬蜱向人类传播伯氏疏螺旋体狭义种的风险
Transmission risk of Borrelia burgdorferi sensu lato from Ixodes ricinus ticks to humans in southwest Germany.
作者信息
Maiwald M, Oehme R, March O, Petney T N, Kimmig P, Naser K, Zappe H A, Hassler D, von Knebel Doeberitz M
机构信息
Hygiene-Institut der Universität, Abt. Hygiene und Med. Mikrobiologie, Heidelberg, Germany.
出版信息
Epidemiol Infect. 1998 Aug;121(1):103-8. doi: 10.1017/s0950268898008929.
The risk of Borrelia burgdorferi infection and the value of antibiotic prophylaxis after tick bite are controversial. In this study, performed in two areas of southwestern Germany, ticks were collected from 730 patients and examined by the polymerase chain reaction (PCR) for B. burgdorferi. To assess whether transmission of B. burgdorferi occurred, the patients were clinically and serologically examined after tick removal and during follow-up examinations. Data from all tick bites gave a total transmission rate of 2.6% (19 patients). Eighty-four ticks (11.3%) were PCR positive. Transmission occurred to 16 (26.7%) of 60 patients who were initially seronegative and could be followed up after the bite of an infected tick. These results indicate that the transmission rate from infected ticks in Europe is higher than previously assumed. Examination of ticks and antibiotic prophylaxis in the case of positivity appears to be indicated.
伯氏疏螺旋体感染的风险以及蜱叮咬后抗生素预防的价值存在争议。在德国西南部两个地区进行的这项研究中，从730名患者身上采集蜱虫，并通过聚合酶链反应（PCR）检测伯氏疏螺旋体。为评估伯氏疏螺旋体是否发生传播，在蜱虫移除后以及随访检查期间对患者进行临床和血清学检查。所有蜱叮咬的数据得出总传播率为2.6%（19名患者）。84只蜱（11.3%）PCR呈阳性。在最初血清学阴性且在被感染蜱叮咬后能够进行随访的60名患者中，有16名（26.7%）发生了传播。这些结果表明，欧洲感染蜱的传播率高于先前的假设。蜱虫检查以及在阳性情况下进行抗生素预防似乎是有必要的。
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