Bayesian linkage analysis, or: how I learned to stop worrying and love the posterior probability of linkage.
作者信息
Vieland V J
机构信息
Department of Preventive Medicine, Division of Biostatistics, University of Iowa College of Medicine, Iowa City, USA.
出版信息
Am J Hum Genet. 1998 Oct;63(4):947-54. doi: 10.1086/302076.
Abstract
摘要
相似文献
1
Bayesian linkage analysis, or: how I learned to stop worrying and love the posterior probability of linkage.贝叶斯连锁分析，或者说：我是如何学会不再担忧并爱上连锁的后验概率的。
Am J Hum Genet. 1998 Oct;63(4):947-54. doi: 10.1086/302076.
2
Two-locus linkage analysis using recombinant inbred strains and Bayes' theorem.使用重组近交系和贝叶斯定理进行双基因座连锁分析。
Genetics. 1990 Sep;126(1):277-84. doi: 10.1093/genetics/126.1.277.
3
A combined test of linkage heterogeneity.连锁异质性的联合检验。
Am J Hum Genet. 1994 Oct;55(4):841-8.
4
A new method for computing the multipoint posterior probability of linkage.一种计算连锁多点后验概率的新方法。
Hum Hered. 2004;57(2):90-9. doi: 10.1159/000077546.
5
Computation of the posterior probability of linkage using 'high effect' genetic model priors.使用“高效应”遗传模型先验概率计算连锁的后验概率。
Hum Hered. 2008;66(1):25-34. doi: 10.1159/000114163. Epub 2008 Jan 28.
6
[Bayesian statistics-based method for genetic linkage analysis].基于贝叶斯统计的基因连锁分析方法
Yi Chuan. 2006 Sep;28(9):1117-22. doi: 10.1360/yc-006-1117.
7
A Bayesian approach to replication of linkage findings.一种用于连锁研究结果复制的贝叶斯方法。
Genet Epidemiol. 1999;17 Suppl 1:S749-54. doi: 10.1002/gepi.13701707123.
8
Transmission disequilibrium, family controls, and great expectations.传递不平衡、家族对照与过高期望。
Am J Hum Genet. 1998 Oct;63(4):935-41. doi: 10.1086/302077.
9
Statistical inference-Bayesian and non-Bayesian.统计推断——贝叶斯推断与非贝叶斯推断。
Am J Hum Genet. 1977 Jan;29(1):107-8.
10
The number of families required to detect or exclude linkage heterogeneity.检测或排除连锁异质性所需的家系数量。
Am J Hum Genet. 1986 Aug;39(2):159-65.
引用本文的文献
1
Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More Than Other Broad Autism Phenotype Traits.与其他广泛的自闭症表型特征相比，狭义与广义表型定义对语言遗传分析的影响更大。
Res Sq. 2025 May 6:rs.3.rs-5457750. doi: 10.21203/rs.3.rs-5457750/v1.
2
A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees.全基因组连锁研究在扩展的家系中自闭症谱系障碍和广泛自闭症表型的研究。
J Neurodev Disord. 2018 Jun 11;10(1):20. doi: 10.1186/s11689-018-9238-9.
3
Behavioral and Molecular Genetics of Reading-Related AM and FM Detection Thresholds.阅读相关的调幅和调频检测阈值的行为与分子遗传学
Behav Genet. 2017 Mar;47(2):193-201. doi: 10.1007/s10519-016-9821-3. Epub 2016 Nov 9.
4
Evaluation of a bayesian model integration-based method for censored data.一种基于贝叶斯模型整合的删失数据方法的评估
Hum Hered. 2012;74(1):1-11. doi: 10.1159/000342707. Epub 2012 Sep 26.
5
Multivariate analysis of anxiety disorders yields further evidence of linkage to chromosomes 4q21 and 7p in panic disorder families.对焦虑障碍的多变量分析为惊恐障碍家族与染色体 4q21 和 7p 的联系提供了进一步证据。
Am J Med Genet B Neuropsychiatr Genet. 2012 Apr;159B(3):274-80. doi: 10.1002/ajmg.b.32024. Epub 2012 Jan 17.
6
KELVIN: a software package for rigorous measurement of statistical evidence in human genetics.凯尔文：一款用于精确测量人类遗传学统计证据的软件包。
Hum Hered. 2011;72(4):276-88. doi: 10.1159/000330634. Epub 2011 Dec 23.
7
Using parametric multipoint lods and mods for linkage analysis requires a shift in statistical thinking.使用参数多点对数优势评分（LODs）和模型进行连锁分析需要统计学思维的转变。
Hum Hered. 2011;72(4):264-75. doi: 10.1159/000331463. Epub 2011 Dec 23.
8
Novel method for combined linkage and genome-wide association analysis finds evidence of distinct genetic architecture for two subtypes of autism.一种新的联合连锁和全基因组关联分析方法发现了两种自闭症亚型具有不同遗传结构的证据。
J Neurodev Disord. 2011 Jun;3(2):113-23. doi: 10.1007/s11689-011-9072-9. Epub 2011 Jan 19.
9
Combined linkage and linkage disequilibrium analysis of a motor speech phenotype within families ascertained for autism risk loci.针对自闭症风险基因座确定的家系中运动性言语表型的连锁与连锁不平衡联合分析。
J Neurodev Disord. 2010 Dec;2(4):210-223. doi: 10.1007/s11689-010-9063-2. Epub 2010 Oct 12.
10
Data integration in genetics and genomics: methods and challenges.遗传学与基因组学中的数据整合：方法与挑战
Hum Genomics Proteomics. 2009 Jan 12;2009:869093. doi: 10.4061/2009/869093.
本文引用的文献
1
Some comments on the statistical methods used in linkage investigations.关于连锁研究中使用的统计方法的一些评论。
Am J Hum Genet. 1959 Dec;11(4):289-304.
2
Sequential tests for the detection of linkage.用于检测连锁的序贯检验。
Am J Hum Genet. 1955 Sep;7(3):277-318.
3
The power to detect linkage in complex disease by means of simple LOD-score analyses.通过简单的对数优势分数分析来检测复杂疾病中连锁关系的能力。
Am J Hum Genet. 1998 Sep;63(3):870-9. doi: 10.1086/301997.
4
A Bayesian approach to multipoint mapping in nuclear families.一种用于核心家庭多点定位的贝叶斯方法。
Genet Epidemiol. 1997;14(6):903-8. doi: 10.1002/(SICI)1098-2272(1997)14:6<903::AID-GEPI57>3.0.CO;2-Q.
5
The problem of ascertainment for linkage analysis.连锁分析的确证问题。
Am J Hum Genet. 1996 May;58(5):1072-84.
6
Lods, wrods, and mods: the interpretation of lod scores calculated under different models.
Genet Epidemiol. 1994;11(4):329-42. doi: 10.1002/gepi.1370110403.
7
Posterior probability of linkage and maximal lod score.
Ann Hum Genet. 1995 Jan;59(1):123-32. doi: 10.1111/j.1469-1809.1995.tb01610.x.
8
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results.复杂性状的基因剖析：解读和报告连锁结果的指南。
Nat Genet. 1995 Nov;11(3):241-7. doi: 10.1038/ng1195-241.
9
A resolution of the ascertainment sampling problem. I. Theory.确定抽样问题的一种解决方案。I. 理论
Theor Popul Biol. 1986 Dec;30(3):388-412. doi: 10.1016/0040-5809(86)90042-0.
10
Effects of misspecifying genetic parameters in lod score analysis.连锁分析中基因参数误设的影响。
Biometrics. 1986 Jun;42(2):393-9.
Zotero 插件