DeBowes L J
Department of Clinical Sciences, Veterinary Medical Teaching Hospital, Kansas State University, Manhattan, USA.
Vet Clin North Am Small Anim Pract. 1998 Sep;28(5):1057-62. doi: 10.1016/s0195-5616(98)50102-7.
Chronic exposure to periodontal pathogens results in the continued stimulation of an immune and nonimmune response by the host. The cytokines and other inflammatory mediators produced in gingivitis/periodontitis result in local tissue destruction and may reach significant levels affecting the cardiovascular system or placental tissues. The oral cavity may also serve as a direct reservoir for bacterial contamination of the lungs with subsequent development of bacterial pneumonia.
