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患有瘙痒症的犬类和无皮肤问题的犬类皮下脂肪及血浆中的脂肪酸谱。

The fatty acid profile of subcutaneous fat and blood plasma in pruritic dogs and dogs without skin problems.

作者信息

Taugbøl O, Baddaky-Taugbøl B, Saarem K

机构信息

Department of Biochemistry, Physiology and Nutrition, Norwegian School of Veterinary Science, Oslo, Norway.

出版信息

Can J Vet Res. 1998 Oct;62(4):275-8.

Abstract

The purpose of this study was to investigate the concentration of polyunsaturated fatty acids (PUFAs) in subcutaneous fat and the relative amounts of PUFAs in plasma in two groups of dogs. Group 1 included dogs with a good skin and coat condition. Group 2 was comprised of dogs with pruritus and compatible clinical signs of atopy. The fatty acid composition of the total lipid fraction was analyzed by gas chromatography. In subcutaneous fat, the concentration of adrenic acid (22:4n-6) was lower in the group of pruritic dogs compared to dogs with healthy skin. The amount of dihomogammalinolenic acid (20:3n-6; DGLA) in plasma lipids from pruritic dogs was higher than in dogs without skin problems.

摘要

本研究的目的是调查两组犬皮下脂肪中多不饱和脂肪酸(PUFA)的浓度以及血浆中PUFA的相对含量。第1组包括皮肤和被毛状况良好的犬。第2组由患有瘙痒症且有特应性皮炎相关临床症状的犬组成。通过气相色谱法分析总脂质部分的脂肪酸组成。在皮下脂肪中,瘙痒犬组的肾上腺酸(22:4n-6)浓度低于皮肤健康的犬。瘙痒犬血浆脂质中的二高γ-亚麻酸(20:3n-6;DGLA)含量高于无皮肤问题的犬。

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