Lari N, Cavallini M, Rindi L, Iona E, Fattorini L, Garzelli C
Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia ed Epidemiologia, Università di Pisa, I-56127 Pisa, Italy.
J Clin Microbiol. 1998 Dec;36(12):3694-7. doi: 10.1128/JCM.36.12.3694-3697.1998.
All but 2 of 63 Mycobacterium avium isolates from distinct geographic areas of Italy exhibited markedly polymorphic, multibanded IS1245 restriction fragment length polymorphism (RFLP) patterns; 2 isolates showed the low-number banding pattern typical of bird isolates. By computer analysis, 41 distinct IS1245 patterns and 10 clusters of essentially identical strains were detected; 40% of the 63 isolates showed genetic relatedness, suggesting the existence of a predominant AIDS-associated IS1245 RFLP pattern.
从意大利不同地理区域分离出的63株鸟分枝杆菌中,除2株外,其余菌株均呈现出明显多态性的多条带IS1245限制性片段长度多态性(RFLP)图谱;2株菌株呈现出鸟类分离株典型的少条带模式。通过计算机分析,检测到41种不同的IS1245图谱和10个基本相同菌株的簇;63株分离株中有40%显示出遗传相关性,这表明存在一种主要的与艾滋病相关的IS1245 RFLP模式。