连续监测血培养系统在导管相关败血症诊断中的应用。
The use of continuous monitoring blood culture systems in the diagnosis of catheter related sepsis.
作者信息
Rogers M S, Oppenheim B A
机构信息
Public Health Laboratory, Withington Hospital, West Didsbury, Manchester, UK.
出版信息
J Clin Pathol. 1998 Aug;51(8):635-7. doi: 10.1136/jcp.51.8.635.
Abstract
AIM
To assess whether the information provided by automated continuous monitoring blood culture systems could aid in the diagnosis of catheter related sepsis.
METHODS
Serial dilutions of a strain of coagulase negative staphylococcus were inoculated into the BacT/Alert blood culture system. Blood culture results for seven patients with possible catheter related sepsis from coagulase negative staphylococci were reviewed.
RESULTS
Time to positivity and length of lag period were strongly related to the concentration of bacteria inoculated (average decrease of 1.5 hours to positivity for each 10-fold increase in concentration). Time to positivity and length of lag period were significantly shorter for central line blood cultures than for those taken from peripheral sites.
CONCLUSIONS
Using data already measured by continuous monitoring blood culture systems may provide a simple alternative to quantitative blood cultures for the diagnosis of catheter related sepsis.
摘要
目的
评估自动连续监测血培养系统提供的信息是否有助于诊断导管相关败血症。
方法
将一株凝固酶阴性葡萄球菌进行系列稀释后接种到BacT/Alert血培养系统中。回顾了7例可能由凝固酶阴性葡萄球菌引起的导管相关败血症患者的血培养结果。
结果
阳性时间和延迟期长度与接种细菌的浓度密切相关（浓度每增加10倍，阳性时间平均减少1.5小时）。中心静脉血培养的阳性时间和延迟期长度明显短于外周血培养。
结论
利用连续监测血培养系统已测得的数据，可能为诊断导管相关败血症提供一种简单的定量血培养替代方法。
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