Hodges P E, McKee A H, Davis B P, Payne W E, Garrels J I
Proteome Inc., 100 Cummings Center, Suite 435M, Beverly, MA 01915, USA.
Nucleic Acids Res. 1999 Jan 1;27(1):69-73. doi: 10.1093/nar/27.1.69.
The Yeast Proteome Database (YPD) is a model for the organization and presentation of comprehensive protein information. Based on the detailed curation of the scientific literature for the yeast Saccharomyces cerevisiae, YPD contains more than 50 000 annotations lines derived from the review of 8500 research publications. The information concerning each of the approximately 6100 yeast proteins is structured around a convenient one-page format, the Yeast Protein Report, with additional information provided as pop-up windows. Protein classification schema have been revised this year, defining each protein's cellular role, function and pathway, and adding a Functional to the Yeast Protein Report. These changes provide the user with a succinct summary of the protein's function and its place in the biology of the cell, and they enhance the power of YPD Search functions. Precalculated sequence alignments have been added, to provide a crossover point for comparative genomics. The first transcript profiling data has been integrated into the YPD Protein Reports, providing the framework for the presentation of genome-wide functional data. The Yeast Proteome Database can be accessed on the Web at http://www.proteome.com/YPDhome.html
酵母蛋白质组数据库（YPD）是一个用于组织和呈现全面蛋白质信息的模型。基于对酿酒酵母科学文献的详细整理，YPD包含了从8500篇研究出版物的综述中得出的50000多条注释信息。关于大约6100种酵母蛋白质中每一种的信息都围绕一种便捷的单页格式——酵母蛋白质报告进行组织，额外信息以弹出窗口的形式提供。今年对蛋白质分类模式进行了修订，定义了每种蛋白质的细胞作用、功能和途径，并在酵母蛋白质报告中增加了“功能”一项。这些变化为用户提供了蛋白质功能及其在细胞生物学中位置的简洁总结，同时增强了YPD搜索功能的能力。已添加预先计算的序列比对，为比较基因组学提供一个交叉点。首批转录谱数据已整合到YPD蛋白质报告中，为呈现全基因组功能数据提供了框架。可通过网页http://www.proteome.com/YPDhome.html访问酵母蛋白质组数据库
