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酵母蛋白质数据库(YPD):一个关于酿酒酵母完整蛋白质组的数据库。

Yeast Protein database (YPD): a database for the complete proteome of Saccharomyces cerevisiae.

作者信息

Payne W E, Garrels J I

机构信息

Proteome, Inc., 200 Cummings Center, Suite 425C, Beverly, MA 01915, USA.

出版信息

Nucleic Acids Res. 1997 Jan 1;25(1):57-62. doi: 10.1093/nar/25.1.57.

Abstract

The Yeast Protein Database (YPD) is a database for the proteins of the budding yeast,Saccharomyces cerevisiae. YPD is the first annotated database for the complete proteome of any organism. Now that the complete genome sequence of yeast is available, YPD contains entries for each of the characterized proteins and for each of the uncharacterized proteins predicted from the sequence. Contained in YPD are the calculated properties of each protein such as molecular weight and isoelectric point, experimentally determined properties such as subcellular localization and post-translational modifications, and extensive annotations from the yeast literature. YPD contains 25 000 lines of textual annotation that describe the known functions, mutant phenotypes, interactions, and other properties for the approximately 6000 proteins in the yeast proteome. The information in YPD is updated daily, and it is available on the World Wide Web at http://www.proteome.com/YPDhome.html .

摘要

酵母蛋白质数据库(YPD)是一个关于芽殖酵母酿酒酵母蛋白质的数据库。YPD是首个针对任何生物体完整蛋白质组的注释数据库。鉴于酵母的完整基因组序列已可得,YPD包含了每个已鉴定蛋白质以及从序列预测出的每个未鉴定蛋白质的条目。YPD中包含每个蛋白质的计算属性,如分子量和等电点,实验确定的属性,如亚细胞定位和翻译后修饰,以及来自酵母文献的大量注释。YPD包含25000行文本注释,描述了酵母蛋白质组中约6000种蛋白质的已知功能、突变体表型、相互作用及其他属性。YPD中的信息每日更新,可通过万维网在http://www.proteome.com/YPDhome.html获取。

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