Luper S
Southwest College of Naturopathic Medicine: 2140 East Broadway Rd. Tempe, AZ 85282, USA.
Altern Med Rev. 1998 Dec;3(6):410-21.
Botanicals have been used traditionally by herbalists and indigenous healers worldwide for the prevention and treatment of liver disease. Clinical research in this century has confirmed the efficacy of several plants in the treatment of liver disease. Basic scientific research has uncovered the mechanisms by which some plants afford their therapeutic effects. Silybum marianum (milk thistle) has been shown to have clinical applications in the treatment of toxic hepatitis, fatty liver, cirrhosis, ischemic injury, radiation toxicity, and viral hepatitis via its antioxidative, anti-lipid peroxidative, antifibrotic, anti-inflammatory, immunomodulating, and liver regenerating effects. Picrorhiza kurroa, though less well researched than Silybum, appears to have similar applications and mechanisms of action. When compared with Silybum, the hepatoprotective effect of Picrorhiza was found to be similar, or in many cases, superior to the effect of Silybum.
世界各地的草药医生和传统治疗师一直以来都在传统医学中使用植物药来预防和治疗肝脏疾病。本世纪的临床研究证实了几种植物在治疗肝脏疾病方面的功效。基础科学研究揭示了一些植物发挥治疗作用的机制。水飞蓟已被证明通过其抗氧化、抗脂质过氧化、抗纤维化、抗炎、免疫调节和肝脏再生作用，在治疗中毒性肝炎、脂肪肝、肝硬化、缺血性损伤、辐射毒性和病毒性肝炎方面具有临床应用价值。胡黄连虽然研究不如水飞蓟充分，但似乎具有类似的应用和作用机制。与水飞蓟相比，发现胡黄连的肝脏保护作用相似，而且在许多情况下优于水飞蓟的作用。
