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结膜松弛症:文献综述及可能的病理生理学

Conjunctivochalasis: literature review and possible pathophysiology.

作者信息

Meller D, Tseng S C

机构信息

The Ocular Surface and Tear Center, Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida 33136, USA.

出版信息

Surv Ophthalmol. 1998 Nov-Dec;43(3):225-32. doi: 10.1016/s0039-6257(98)00037-x.

DOI:10.1016/s0039-6257(98)00037-x
PMID:9862310
Abstract

Conjunctivochalasis, defined as a redundant conjunctiva typically located between the globe and the lower eyelid, is not uncommon. However, it is often overlooked, as it may be considered a normal senile change. Conjunctivochalasis can cause a spectrum of symptoms, ranging from aggravation of a dry eye at the mild stage, to disturbance of tear outflow at the moderate stage, and exposure problems at the severe stage. Clinical recognition of its pathogenic role helps differentiate conjunctivochalasis from other diseases that may generate similar symptoms. For symptomatic patients, topical lubricants can be tried, but they are frequently unsuccessful, and surgical excision may be required. To guide future investigation into the clinical significance of conjunctivochalasis, a comprehensive grading system and a hypothetical pathophysiology are proposed. Special attention is given to the relationship of conjunctivochalasis to tear dynamics.

摘要

结膜松弛症是指通常位于眼球与下眼睑之间的多余结膜,并不罕见。然而,它常被忽视,因为可能被视为正常的衰老变化。结膜松弛症可引发一系列症状,从轻度阶段的干眼加重,到中度阶段的泪液流出障碍,再到重度阶段的暴露问题。临床认识其致病作用有助于将结膜松弛症与可能产生类似症状的其他疾病区分开来。对于有症状的患者,可以尝试使用局部润滑剂,但往往效果不佳,可能需要手术切除。为指导未来对结膜松弛症临床意义的研究,提出了一个综合分级系统和一种假设的病理生理学。特别关注结膜松弛症与泪液动力学的关系。

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