Combemale P, Faisant M, Guennoc B, Dupin M, Heyraud J D
Department of Dermatology, Military Hospital Desgenettes, Lyon, France.
J Dermatol. 1998 Nov;25(11):747-53. doi: 10.1111/j.1346-8138.1998.tb02495.x.
Erythema dyschromicum perstans (EDP), described by Convit et al. in 1961, is a rare dermatosis. Its relationship with ashy dermatosis (AD), described by Ramirez in 1957, is still a matter of debate. We report a typical case of EDP. The patient, of North African origin, had a dyschromic (hypo- and hyperpigmented) eruption on the chest and limbs for 2 years. The lesions were occasionally surrounded by a papular border which spread slowly and centrifugally. Histological examination showed a lichenoid infiltrate. A carcinoma of the lung was simultaneously discovered. No treatment was given, EDP is infrequent and often considered identical to ashy dermatosis in the literature. However, the clinical aspects of the two diseases differ. The main features of these two diseases are reviewed and compared on the basis of a literature review. We conclude that EDP and AD are distinct clinical entities.
持久性色素异常性红斑（EDP）由康维特等人于1961年描述，是一种罕见的皮肤病。它与拉米雷斯于1957年描述的灰色皮肤病（AD）之间的关系仍存在争议。我们报告一例典型的EDP病例。该患者来自北非，胸部和四肢出现色素异常（色素减退和色素沉着）皮疹已有2年。皮损偶尔被丘疹性边缘环绕，呈缓慢离心性扩散。组织学检查显示苔藓样浸润。同时发现了一例肺癌。未给予治疗，EDP并不常见，在文献中常被认为与灰色皮肤病相同。然而，这两种疾病的临床特征有所不同。基于文献综述，对这两种疾病的主要特征进行了回顾和比较。我们得出结论，EDP和AD是不同的临床实体。
