Amarapurkar A D, Vora I M, Dhawan P S
Department of Pathology, T N Medical College, BYL Nair Charitable Hospital, Mumbai, India.
Indian J Pathol Microbiol. 1998 Oct;41(4):431-5.
Contrary to earlier definition of Barrett's oesophagus which referred to the presence of metaplastic columnar epithelium of either gastric or intestinal type, the new definition lays stress on presence of specialised columnar epithelium (SEC) with goblet cells. Hence this study was carried out to determine the frequency of specialised columnar epithelium in Indian population. 150 cases of dyspepsia underwent esophagogatro duodenoscopy with esophageal biopsy. Slides were stained with routine H and E stain and alcian blue-PAS stain. Histologically, esophagitis was found in 75 (50%) and columnar epithelium-gastric type in 63 (42%) cases only 4 (2.6%) cases showed presence of specialised columnar epithelium which were labelled as Barrett's esophagus, giving an incidence of 2.6% in this study.
与早期将巴雷特食管定义为存在胃型或肠型化生柱状上皮不同，新定义强调存在含有杯状细胞的特殊柱状上皮（SEC）。因此，本研究旨在确定印度人群中特殊柱状上皮的发生率。150例消化不良患者接受了食管胃十二指肠镜检查及食管活检。玻片用常规苏木精和伊红染色以及阿尔辛蓝-过碘酸雪夫染色。组织学上，75例（50%）发现有食管炎，63例（42%）有胃型柱状上皮，只有4例（2.6%）显示存在特殊柱状上皮，被标记为巴雷特食管，本研究中的发生率为2.6%。
