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降低视力损害和失明的风险。

Lowering the risk of visual impairment and blindness.

作者信息

Cunha-Vaz J

机构信息

Department of Ophthalmology, University Hospital and Institute of Biomedical Research on Light and Image, Coimbra, Portugal.

出版信息

Diabet Med. 1998;15 Suppl 4:S47-50. doi: 10.1002/(sici)1096-9136(1998120)15:4+<s47::aid-dia739>3.3.co;2-j.

Abstract

Diabetic retinopathy remains the leading cause of visual disability and blindness among professionally active adults in economically developed societies, which is of particular concern because the prevalence and incidence of Type 2 diabetes mellitus is expected to increase sharply during the next decade. Retinopathy is fundamentally similar in Type 1 and Type 2 diabetes mellitus, and it is widely accepted that if detected and treated early, loss of vision and blindness from diabetic retinopathy may be prevented. Studies such as the Diabetes Control and Complications Trial (DCCT), the United Kingdom Prospective Diabetes Study Group (UKPDS), the Diabetic Retinopathy Study (DRS) and the Early Treatment Diabetic Retinopathy Study (ETDRS) have established accepted guidelines for the management of diabetic retinopathy. Good metabolic control is particularly important in the early phases of the disease, and will delay the onset of retinopathy and decrease the rate of progression. When advanced stages of retinopathy are reached, laser photocoagulation is effective in decreasing the development to blindness by over 50%. However, preventable blindness still occurs despite the tight control of blood glucose levels and the use of retinal photocoagulation. To reduce the risk of visual impairment and blindness caused by diabetes, diabetic patients must be taught how to control their blood glucose levels, regular eye examinations must be carried out and the conditions for timely laser photocoagulation must be created. The implementation of screening and treatment programmes for visual impairment in diabetes has proved to be worthwhile in terms of costs and health benefits.

摘要

在经济发达社会中,糖尿病视网膜病变仍是职业活跃成年人视力残疾和失明的主要原因,这尤其令人担忧,因为预计在未来十年中2型糖尿病的患病率和发病率将急剧上升。1型和2型糖尿病中的视网膜病变在本质上相似,并且人们普遍认为,如果早期发现并治疗,糖尿病视网膜病变导致的视力丧失和失明是可以预防的。诸如糖尿病控制与并发症试验(DCCT)、英国前瞻性糖尿病研究小组(UKPDS)、糖尿病视网膜病变研究(DRS)和早期治疗糖尿病视网膜病变研究(ETDRS)等研究已经确立了糖尿病视网膜病变管理的公认指南。良好的代谢控制在疾病早期尤为重要,将延迟视网膜病变的发作并降低进展速度。当达到视网膜病变的晚期阶段时,激光光凝术在降低失明发生率方面有效率超过50%。然而,尽管严格控制血糖水平并使用视网膜光凝术,可预防的失明仍然会发生。为降低糖尿病导致的视力损害和失明风险,必须教导糖尿病患者如何控制血糖水平,必须定期进行眼部检查,并创造及时进行激光光凝术的条件。事实证明,实施糖尿病视力损害筛查和治疗方案在成本和健康效益方面是值得的。

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