Baráthová H, Betina V
Folia Microbiol (Praha). 1976;21(5):355-61. doi: 10.1007/BF02876961.
The effect of antibiotics and metabolic inhibitors on mycelial growth of Botrytis cinera was followed. Inhibitors of protein synthesis, chloramphenicol, erythromycin and tetracycline inhibit growth or sporulation of Botrytis cinera. Ethidium bromide, 5-fluorouracil, phenylethylalcohol and K 20 cause granulation, vacuolization and undulation of hyphase. 2,4-Dinitrophenol, boromycin, macrotetrolides, monensin, scopathricin and TX2 at subfungistatic concentrations induce intensive branching of hyphal tips i.e. at the site of synthesis of the cell wall. In older hyphase grown in the absence of the antibiotics the branching begins after their addition, particularly in the septum region. When comparing the results referred to here with those obtained previously and on the basis of literature data it may be assumed that the changes in polarity of growth of Botrytis cinerea might be caused primarily or secondarily by impairing membrane functions and formation of cell walls.
研究了抗生素和代谢抑制剂对灰葡萄孢菌菌丝生长的影响。蛋白质合成抑制剂氯霉素、红霉素和四环素可抑制灰葡萄孢菌的生长或孢子形成。溴化乙锭、5-氟尿嘧啶、苯乙醇和K20会导致菌丝出现颗粒化、空泡化和波动现象。亚抑菌浓度的2,4-二硝基苯酚、硼霉素、大环四内酯、莫能菌素、司帕沙星和TX2会诱导菌丝尖端强烈分支，即细胞壁合成部位。在无抗生素条件下生长的较老菌丝中，添加抗生素后开始出现分支，尤其是在隔膜区域。将此处所述结果与先前获得的结果以及文献数据进行比较后，可以认为灰葡萄孢菌生长极性的变化可能主要或次要由膜功能受损和细胞壁形成引起。
