Eickbush T H
Department of Biology, University of Rochester, Rochester, New York 14627, USA.
Curr Biol. 1999 Jan 14;9(1):R11-4. doi: 10.1016/s0960-9822(99)80034-7.
A mobile bacterial group II intron can integrate into DNA by the reverse splicing into a target site of its RNA transcript, which then acts as a template for DNA synthesis by an encoded reverse transcriptase. Mobility does not require homologous recombination, which has important practical and evolutionary implications.
一种可移动的细菌II类内含子可通过反向剪接整合到其RNA转录本的靶位点的DNA中，该靶位点随后作为由编码的逆转录酶进行DNA合成的模板。移动性不需要同源重组，这具有重要的实际和进化意义。
