Frank M J, Schaffner W
JAMA. 1976 Nov 22;236(21):2418-9.
During January and February 1975, nine patients on a single ward of a rural Tennessee hospital unexpectedly developed sepsis. The aseptic technique employed in the management of intravenous infusions was implicated. Pseudomonas cepacia was recovered from the following: bloodstream, inuse intravenous infusions and the antiseptic, aqueous benzalkonium chloride. The outbreak again calls attention to the infection risk associated with the use of this product. Selection of less hazardous antiseptics and disinfectants is strongly recommended.
1975年1月和2月期间，田纳西州一家乡村医院的一个病房里有9名患者意外发生败血症。静脉输液管理中采用的无菌技术受到牵连。从以下方面分离出洋葱伯克霍尔德菌：血液、正在使用的静脉输液以及防腐剂苯扎氯铵水溶液。此次疫情再次提醒人们注意使用该产品所带来的感染风险。强烈建议选用危害较小的防腐剂和消毒剂。
