[Epidemiological data on toxoplasmosis. The aspects of congenital toxoplasmosis].

The aim of the present study was to get a real image about Toxoplasma gondii infection of pregnant woman and the consequence for her child in Moldavia area. There were studied: 224 pregnant women with pathological pregnancies comparing with 347 apparently healthy pregnant women; 1422 newborns; 223 children with mental retardation and visual pathology comparing with 129 apparently healthy children. There were used the following serological methods: indirect immunofluorescent assay, direct agglutination test, immunosorbent agglutination assay (ISAGA). The following results were obtained: 1) a high sero-prevalence of T. gondii antibodies among pregnant women (43.9%)--most of them being chronic infections; 2) 0.6% pregnant women with acute toxoplasmosis in the first trimester of their pregnancies, situation with great danger for the unborn child; 3) a 7.1% degrees of participation of T.gondii infection to the etiology of spontaneous abortion; 4) a high seroprevalence of T.gondii antibodies among children with mental retardation (66.4%) and visual pathology (37.4%) comparing with the group of apparently healthy children (9.3%). The conclusion resulting from this data is that toxoplasmosis demands more attention from our medical world, a national program of prophylaxis including a large screening of pregnant women and/or newborns being able to prevent the severe damages due to congenital toxoplasmosis.