Piecková E, Jesenská Z
Institute of Preventive and Clinical Medicine, Bratislava, Slovakia.
Folia Microbiol (Praha). 1998;43(6):672-8. doi: 10.1007/BF02816388.
The ciliostatic activity of the chloroform-extractable endo- and exometabolites of 5 strains of filamentous fungi--Alternaria sp., Aspergillus glaucus group, Aspergillus versicolor, Cladosporium sphoerospermum, Penicillium sp. and Ulocladium sp.--isolated from molded walls of a dwelling--on tracheal cilia from 1-d-old chicks in vitro was evaluated. Endometabolites of Alternaria sp. and A. versicolor and exometabolites of Ulocladium sp. were the most active, these extracts stopped the ciliary movement within 1 d. The results are discussed in relation to the health status of people living in "moldy" dwellings.
对从一所住宅发霉墙壁上分离出的5种丝状真菌——链格孢属、青霉属、杂色曲霉、球孢枝孢、青霉属和匐柄霉属——的氯仿可提取内、外代谢产物对1日龄雏鸡气管纤毛的体外纤毛抑制活性进行了评估。链格孢属和杂色曲霉的内代谢产物以及匐柄霉属的外代谢产物活性最强,这些提取物在1天内就停止了纤毛运动。结合居住在“发霉”住宅中的人们的健康状况对结果进行了讨论。