Lipton P A, Alvarez P, Eichenbaum H
Department of Psychology, Boston University, Massachusetts 02215, USA.
Neuron. 1999 Feb;22(2):349-59. doi: 10.1016/s0896-6273(00)81095-8.
Firing patterns of neurons in the orbitofrontal cortex (OF) were analyzed in rats trained to perform a task that encouraged incidental associations between distinct odors and the places where their occurrence was detected. Many of the neurons fired differentially when the animals were at a particular location or sampled particular odors. Furthermore, a substantial fraction of the cells exhibited odor-specific firing patterns prior to odor presentation, when the animal arrived at a location associated with that odor. These findings suggest that neurons in the OF encode cross-modal associations between odors and locations within long-term memory.
在经过训练以执行一项任务的大鼠中，分析了眶额皮质（OF）中神经元的放电模式。该任务鼓励不同气味与其被检测到的位置之间形成偶然关联。当动物处于特定位置或嗅到特定气味时，许多神经元会产生不同的放电。此外，当动物到达与特定气味相关的位置时，相当一部分细胞在气味呈现之前就表现出特定气味的放电模式。这些发现表明，眶额皮质中的神经元在长期记忆中编码气味与位置之间的跨模态关联。
