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淋巴细胞中的促炎因子(LpIF)能否解释这些细胞在急性炎症中的作用?

Does the pro-inflammatory factor in lymphocytes (LpIF) explain the role of these cells in acute inflammation?

作者信息

Santos R R, Leme J G, Ferreira S H, Bechara G H, Sudo L

出版信息

Agents Actions. 1976 Nov;6(6):690-3. doi: 10.1007/BF02026089.

Abstract

Lymphocytes produce a pro-inflammatory factor, which modulates the development of acute inflammation. Injection of lymphocytes or products, obtained from either rats, dogs or rabbits, caused a restoration of inflammatory responses in leukopenic rats which are hyporeactive to various inflammatory stimuli. In vitro incubation of viable lymphocytes with homologous and heterologous anti-lymphocyte sera abolished the ability of the cells to restore the inhibited inflammatory reactions.

摘要

淋巴细胞产生一种促炎因子,该因子可调节急性炎症的发展。注射从大鼠、狗或兔子获取的淋巴细胞或其产物,可使对白血球减少且对各种炎症刺激反应低下的大鼠恢复炎症反应。将活淋巴细胞与同源和异源抗淋巴细胞血清进行体外培养,会消除细胞恢复受抑制炎症反应的能力。

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