Seidman J G, Leder P
Nature. 1978;276(5690):790-5. doi: 10.1038/276790a0.
Cloned segments of mouse chromosomal DNA provide direct evidence for the somatic rearrangement of kappa variable and constant region genes in antibody producing cells. This rearrangement apparently affects only one member of an allelic pair of light chain genes.
小鼠染色体DNA的克隆片段为抗体产生细胞中κ可变区和恒定区基因的体细胞重排提供了直接证据。这种重排显然只影响轻链基因等位基因对中的一个成员。