Kozinn P J, Taschdjian C L, Goldberg P K, Protzmann W P, MacKenzie D W, Remington J S, Anderson S, Seelig M S
Am J Clin Pathol. 1978 Dec;70(6):893-8. doi: 10.1093/ajcp/70.6.893.
Candida antibody tests for systemic candidiasis were conducted on 53 sera from patients with the disease and 170 sera from control patients by agar gel diffusion, counterimmunoelectrophoresis (CIE), latex agglutination, and whole-cell agglutination. The agar gel diffusion test and CIE had sensitivity, specificity, and efficiency of approximately 90%. The whole-cell agglutination test scored significantly lower, whereas the latex test scored in between. The agar gel diffusion test had the highest reproducibility and the whole-cell agglutination test the lowest in tests of identical sera by six independent laboratories. The agar gel diffusion and CIE tests make significant contributions to the diagnosis of systemic candidiasis.
通过琼脂凝胶扩散法、对流免疫电泳（CIE）、乳胶凝集试验和全细胞凝集试验，对53例患有全身性念珠菌病患者的血清以及170例对照患者的血清进行了全身性念珠菌病的念珠菌抗体检测。琼脂凝胶扩散试验和CIE的敏感性、特异性和效率约为90%。全细胞凝集试验得分显著较低，而乳胶试验得分介于两者之间。在六个独立实验室对相同血清进行的检测中，琼脂凝胶扩散试验的重复性最高，全细胞凝集试验的重复性最低。琼脂凝胶扩散试验和CIE试验对全身性念珠菌病的诊断有重要贡献。
