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一些十字花科植物(哈拉氏双带荠和小果芝麻菜)的抗菌成分。

Antimicrobial components of some cruciferae plants (Diplotaxis harra Forsk. and Erucaria microcarpa Boiss.).

作者信息

Hashem F A, Saleh M M

机构信息

Pharmaceutical Science Department, National Research Centre, Dokki, Cairo, Egypt.

出版信息

Phytother Res. 1999 Jun;13(4):329-32. doi: 10.1002/(SICI)1099-1573(199906)13:4<329::AID-PTR458>3.0.CO;2-U.

Abstract

The total herb of Diplotaxis harra Forsk. on treatment with myrosinase produces isopropyl isothiocyanate and 3- butenyl isothiocyanate in addition to (the non-volatile) 2-hydroxy-3-butenyl isothiocyanate which could be obtained as 5-vinyl-2-oxazolidinethione (goitrin) and methyl 4-isothiocyanatobutyrate (Erypestrin). On treating Erucaria microcarpa Boiss, herb with myrosinase, it produces isopropyl isothiocyanate, butyl isothiocyanate and benzyl isothiocyanate in addition to the non-volatile 8-methylsulphinyloctyl isothiocyanate (hirsutin). The plant extracts contain high percentages of arachidonic and palmitic acids, nonadecane, cholesterol, stigmasterol and B-sitosterol. The volatile constituents of D. harra and E. microcarpa showed higher activity against yeasts than Gram +ve, Gram -ve bacteria and fungi. The nonmethylated fatty acids of the two herbs showed higher activity against Gram +ve and Gram -ve bacteria than yeasts and fungi.

摘要

哈拉双带荠(Diplotaxis harra Forsk.)的全草经黑芥子酶处理后,除了可得到5-乙烯基-2-恶唑烷硫酮(甲状腺肿素)和4-异硫氰酸丁酯甲酯(白芥子素)形式的(非挥发性)2-羟基-3-丁烯基异硫氰酸酯外,还会产生异丙基异硫氰酸酯和3-丁烯基异硫氰酸酯。用黑芥子酶处理小果芝麻菜(Erucaria microcarpa Boiss)的全草时,除了非挥发性的8-甲磺酰基辛基异硫氰酸酯(hirsutin)外,还会产生异丙基异硫氰酸酯、丁基异硫氰酸酯和苄基异硫氰酸酯。植物提取物含有高比例的花生四烯酸和棕榈酸、十九烷、胆固醇、豆甾醇和β-谷甾醇。哈拉双带荠和小果芝麻菜的挥发性成分对酵母的活性高于革兰氏阳性菌、革兰氏阴性菌和真菌。这两种草药的非甲基化脂肪酸对革兰氏阳性菌和革兰氏阴性菌的活性高于酵母和真菌。

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