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狭瓣辣木叶片乙醇提取物对豚鼠和小鼠平滑肌的影响。

Effects of ethanol extract of Moringa stenopetala leaves on guinea-pig and mouse smooth muscle.

作者信息

Mekonnen Y

机构信息

Department of Biology, Faculty of Science, Addis Ababa University, P. O.Box 1176, Addis Ababa, Ethiopia.

出版信息

Phytother Res. 1999 Aug;13(5):442-4. doi: 10.1002/(sici)1099-1573(199908/09)13:5<442::aid-ptr476>3.0.co;2-7.

DOI:10.1002/(sici)1099-1573(199908/09)13:5<442::aid-ptr476>3.0.co;2-7
PMID:10441791
Abstract

The fresh leaf ethanol (LE) extract of Moringa stenopetala was tested in guinea-pig ileum and mouse duodenum and in uterus strips. There were significant dose and time dependent reductions of the acetylcholine (AC) response with initial stimulatory effects in both the guinea-pig ileum and the mouse duodenum preparations. Spontaneous rhythmic contractions were greatly reduced, suggesting an antispasmodic property of the crude LE extract. The LE extract showed some oxytocic activity on uterus strips of guinea-pigs and mice. The results are indicative of the traditional use of the leaves of Moringa stenopetala for stomach pain and to expel retained placentae by women.

摘要

对狭瓣辣木的鲜叶乙醇提取物在豚鼠回肠、小鼠十二指肠和子宫条上进行了测试。在豚鼠回肠和小鼠十二指肠制剂中,乙酰胆碱(AC)反应有显著的剂量和时间依赖性降低,最初有刺激作用。自发性节律性收缩大大减少,表明粗乙醇提取物具有解痉特性。乙醇提取物对豚鼠和小鼠的子宫条显示出一定的催产活性。这些结果表明了狭瓣辣木叶在传统上用于治疗胃痛以及妇女排出滞留胎盘的用途。

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