用于近红外激光光凝研究的光学体模材料。

Optical phantom materials for near infrared laser photocoagulation studies.

作者信息

Iizuka M N, Sherar M D, Vitkin I A

机构信息

Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada.

出版信息

Lasers Surg Med. 1999;25(2):159-69. doi: 10.1002/(sici)1096-9101(1999)25:2<159::aid-lsm10>3.0.co;2-v.

DOI:10.1002/(sici)1096-9101(1999)25:2<159::aid-lsm10>3.0.co;2-v

PMID:10455223

Abstract

BACKGROUND AND OBJECTIVE

Phantoms were developed that simulate tissue with dynamic and static optical properties with which to study the effects of laser irradiation.

STUDY DESIGN/MATERIALS AND METHODS: Albumen, agar, and an absorbing dye (Naphthol Green) were combined to form a phantom with heat sensitive optical properties to mimic tissue response. The optical properties of this phantom were measured by using the added absorber technique. A polyacrylamide phantom with static optical properties was designed with the equivalent values of micro(a) and micro'(s) by combining appropriate concentrations of Naphthol Green and Intralipid-10%.

RESULTS

The absorption and reduced scattering coefficient of the phantoms were 0. 50 +/- 0.04 cm(-1) and 2.67 +/- 0.07 cm(-1) respectively, in the native state at 805 nm. In the coagulated state, the absorption and scattering coefficient were 0.7 +/- 0.1 cm(-1) and 13.1 +/- 0.5 cm(-1) respectively.

CONCLUSION

Two phantoms with dynamic or static optical properties were developed with properties similar to tissue. They may be used in future studies of opto-thermal effects in tissues.

摘要