Gutiérrez M, García Marín J F
Vet Pathol. 1999 Sep;36(5):445-8. doi: 10.1354/vp.36-5-445.
An adult Blanca-Celtibérica doe originating from a goat herd with a high prevalence of tuberculosis was presented with respiratory signs. At necropsy, this goat had a diffuse and severe mycotic pneumonia associated with the presence of Cryptococcus neoformans concomitant with pulmonary focal caseous nodules from which Mycobacterium bovis was isolated. Microscopically, the mycotic lesion was a granulomatous pneumonia with many large foamy macrophages containing intracellular yeast bodies. The extensive mycotic changes, their granulomatous nature, and the lack of positive response to different immunologic tests for mycobacterial infection suggested an impaired immune status in this animal.
一只来自结核病高流行率山羊群的成年布兰卡-凯尔特伊比利亚母羊出现了呼吸道症状。尸检时，这只山羊患有弥漫性重度霉菌性肺炎，伴有新型隐球菌，同时还有肺部局灶性干酪样结节，从中分离出了牛分枝杆菌。显微镜下，霉菌性病变为肉芽肿性肺炎，有许多含有细胞内酵母体的大泡沫巨噬细胞。广泛的霉菌性变化、其肉芽肿性质以及对不同分枝杆菌感染免疫检测缺乏阳性反应表明这只动物的免疫状态受损。
