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手工与机械性颈段食管胃吻合术的比较:一项随机试验。

Manual compared with mechanical cervical oesophagogastric anastomosis: a randomised trial.

作者信息

Laterza E, de' Manzoni G, Veraldi G F, Guglielmi A, Tedesco P, Cordiano C

机构信息

First Division of General Surgery, Istituto di Semeiotica Chirurgica, University of Verona, Italy.

出版信息

Eur J Surg. 1999 Nov;165(11):1051-4. doi: 10.1080/110241599750007883.

Abstract

OBJECTIVE

To compare the short and medium term result of hand-sewn and stapled anastomoses after oesophagectomy.

DESIGN

Randomised study.

SETTING

Teaching hospital, Italy.

SUBJECTS

41 patients who required oesophagectomy between February 1993 and December 1996.

INTERVENTIONS

Oesophagectomy and left cervical gastroplasty.

MAIN OUTCOME MEASURES

Mortality and morbidity.

RESULT

21 patients were randomised to have the anastomosis hand-sewn, and 20 to have it stapled. The two groups were comparable. 3 patients died in hospital (2 in the hand-sewn and 1 in the stapled group), and the remainder were followed up a mean of 21 months (range 6-34). There was one clinical leak in the hand-sewn group compared with 3 in the stapled group, and 1 further radiological leak in the stapled group. 2 patients in the hand-sewn and 3 in the stapled group developed strictures.

CONCLUSION

Though the numbers are too small to be assessed statistically, we think that these result are sufficient to persuade us that oesophagogastric anastomoses should be hand-sewn rather than stapled.

摘要

目的

比较食管癌切除术后手工缝合与吻合器吻合的近期和中期结果。

设计

随机研究。

地点

意大利的教学医院。

研究对象

1993年2月至1996年12月期间需要进行食管癌切除术的41例患者。

干预措施

食管癌切除术及左颈部胃成形术。

主要观察指标

死亡率和发病率。

结果

21例患者被随机分配接受手工缝合吻合,20例接受吻合器吻合。两组具有可比性。3例患者在住院期间死亡(手工缝合组2例,吻合器组1例),其余患者平均随访21个月(范围6 - 34个月)。手工缝合组有1例临床吻合口漏,吻合器组有3例,吻合器组还有1例影像学吻合口漏。手工缝合组2例患者和吻合器组3例患者出现狭窄。

结论

尽管样本数量太少无法进行统计学评估,但我们认为这些结果足以使我们相信食管胃吻合应采用手工缝合而非吻合器吻合。

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